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Senior Scientist II, Biologics Purification

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North Chicago, North Chicago
Posted 12 days ago
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Job Description

Join AbbVie’s Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification, you will play a pivotal role in driving drug discovery, collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide. Your expertise will help deliver high-purity bispecific candidates with suitable purity/characteristics to support the advancement of vital in vitro (i.e. drug-like property assays, binding, cell-based assays, etc.) and in vivo studies (i.e. efficacy, non-GLP NHP PK, DRF, etc.). 

Key Responsibilities:

  • Lead the purification of bispecific biologics to support critical research assays and studies
  • Design and execution of robust process development strategies necessary to address production liabilities which factor into future process scalability. 
  • Apply advanced bioprocessing and chromatography techniques at large scale
  • Utilize in silico tools, DOE methodologies, and predictive modeling to optimize protein separation and maximize yield/quality
  • Integrate and manage analytical data using LIMS, ETL tools, and data extraction APIs
  • Collaborate with multidisciplinary teams, translating molecular insights into functional results
  • Stay current with emerging scientific literature to foster innovation and continuous improvement
  • Present findings clearly to diverse audiences and document results with rigor
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