We are seeking an enthusiastic and creative hands-on scientist to join the Cell Culture Process Development group within PDS&T Biologics at AbbVie Bioresearch Center in Worcester, MA. As part of the Cell Culture Development organization, you will support process development and technology transfer activities for cell culture processes, contributing to the clinical manufacturing and commercialization of therapeutic proteins in the AbbVie pipeline. Additionally, the team provides subject matter expertise and experimental support for the production of commercial biologics. The ideal candidate will work effectively both independently and collaboratively within a dynamic team environment.

Key Responsibilities:

• Develop and characterize highly-productive CHO cell culture processes suitable for cGMP biotherapeutic manufacturing within project timelines, performing technical transfer and manufacturing support activities.
• Conceive and execute scientific research and development to significantly improve platform processes and workflows, develop new methods, build technical expertise and deepen scientific understanding.
• Design, execute and analyze cell culture experiments using Design of Experiments (DOE) principles and report data summary packages for multi-variate analysis.
• Work collaboratively and cross-functionally with colleagues in other functional areas (Analytical Development, Cell Line Development, Discovery, Manufacturing and Quality).
• Effectively communicate scientific data and concepts to internal and external audiences through reports, presentations and manuscripts.
• Author and review technical reports, protocols, and other key documents.
• Understand and adhere to corporate standards regarding code of conduct, safety, documentation and GMP compliance.

Preferred Qualifications:

• M.S. in biology, biochemical/chemical engineering or life sciences related disciplines with 2+ years of industrial experience; or B.S. in biochemical/chemical engineering or life sciences related disciplines with 5+ years of industrial experience.
• Hands-on experience with upstream mammalian suspension cell culture using bench scale bioreactors, deep well plates and shake flasks.
• Understanding of cell culture processes (e.g., cell culture process development, process scale up and scale down, recombinant protein production, protein characterization).
• Experience with statistical data analysis tools such as design of experiment, multivariate data analysis and modeling.
• Experience with automated liquid handling systems and high throughput culture is a plus
• Excellent interpersonal and communication skills. Strong scientific curiosity with a passion for problem-solving and optimization. Self-motivated with excellent attention to detail and ability to multi-task. Strong organizational, planning and trouble-shooting skills.