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Scientist I – Bioassay Sciences and Development (all genders) (full- or part-time, temporary for 2 years)

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Ludwigshafen, Ludwigshafen
Posted 11 days ago
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Job Description

The job that makes possibilities real in patients' lives. And yours.

The job that helps you get ahead in life. Moving mountains together.

Welcome to AbbVie! As part of an international company with 48,000 employees worldwide and around 3,000 employees in Germany, you will have the opportunity of addressing some of tomorrows unmet medical needs in close collaboration with your colleagues. Are you passionate about improving global health care? Do you want to contribute to improving patients' quality of life through your expertise? In a challenging work environment that offers opportunities of developing and increasing your own skills? Youve come to the right place!

Moving mountains together – as Scientist I –Bioassay Sciences and Development (all genders)

As a Scientist in the Bioassay Sciences and Development group, you will play a key role in advancing the group’s efforts on targeted mRNA lipid nanoparticles (tLNPs), translating scientific innovation into operational standards, and automating assays for this new modality in a GMP compliant environment. In this lab-based position, you will focus on assay execution and verification of data for running programs, and on optimizing and integrating new modalities and technologies. Responsibilities include the implementation of expression assays, functional potency assays, and PCR applications for the characterization and quality control of innovative therapeutics. Your work will increase throughput, data quality, and process consistency under highly regulated GMP conditions.

Your tasks and responsibilities:

  • Design, optimize, and transfer analytical methods, especially in vitro cell-based bioassays (e.g., expression assays, reporter gene assays, targeted killing assays) and other technologies (e.g., qPCR, ddPCR)
  • Independent performance of reagent qualification, assay validation, sample analysis and test method transfers under good scientific practice and GMP to support release and stability studies especially for early pharmaceutical development of tLNPs
  • Self-dependent authorship of laboratory reports and Standard Operating Procedures (SOPs) in English, including documentation for automated systems, development, and validation reports.
  • Coordinate GMP-relevant laboratory tasks, serve as equipment subject matter expert, oversee equipment qualification. Communicate effectively in meetings and teleconferences, collaborate across sites and departments, and promote best practices in laboratory automation.
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