Alumis Inc is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer – our goal is to fundamentally change the outcomes for these patients.

We are seeking an experienced and motivated Director, Commercial Program Management. In this highly visible, exciting role, you will guide our commercial team in partnership with the molecule development team and cross-functional team leads, providing exceptional program management for our lead molecule envudeucitinib (envu), which disclosed positive Phase 3 data for psoriasis in January 2026. This position will report to the Head of Program and Portfolio Management (PPM).

RESPONSIBILITIES

• Strategic thought partner with the Commercial Lead on Brand Plan and Launch Playbook for lead molecule envudeucitinib (envu)
• Provide Project Management support on envu Launch Readiness Team (eLRT) as well as coordinate and align Commercial workstreams, managing team and workstream activities, including agenda management, meeting facilitation, minutes and tracking of action items and team deliverables
• Facilitate team execution on integrated Launch Playbook, in support of molecule’s strategy and Brand Plan objectives, including timelines, budget, and risks
• Proactively identify, analyze and communicate decision points and risks, framing options within broader molecule context
• Ensure effective communication within functional Commercial team and across cross-functional stakeholders, including molecule Project Team and Executive Committee members, to support good decision-making in fast-paced small company environment
• Act as a vendor liaison, providing contract, requisition processing, and invoice management support, as well as following up with vendor on project updates and status reports, to ensure timely and quality deliverables
• Identify needs and propose solutions to project and portfolio tools, systems and practices to support the growth and evolution of PPM’s capabilities
• Support other business priorities as needed within PPM, including but not limited to potential assignments in research, development, clinical, medical affairs or CMC project or business management
• Manage others as needed

THE IDEAL CANDIDATE

• Minimum 12 years industry experience, with at least 5 years of direct drug development project management (e.g. research, development, CMC, medical affairs, commercial)
• Experience with commercial launch
• Highly skilled in communication, stakeholder management, and influencing without authority, where you are able to effectively interact with, and facilitate complex conversations across the organization
• Excellent critical thinking, verbal and written communication skills, with ability to simplify and integrate multiple cross-functional perspectives and inputs for team
• Agile and flexible: Able to step in, assess situations, and help team to make sound decisions in alignment with program strategy
• Strong organizational skills with critical attention to detail and ability to track to numerous deliverables
• Broad scientific and business acumen in the biotech or pharmaceutical industry, including a strong understanding of cross-functional dependencies
• Proficient with Microsoft Office Suite, as well as project management software such as MS Project and Smartsheets

EDUCATION

• A. or BSc. with MSc., MBA or Ph.D. a plus
• Project Management Professional (PMP) or other PM certification a plus

The salary range for this position is $197,000 USD to $247,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.

This position is located in South San Francisco, CA, with an expectation to be onsite Tuesday through Thursday. 

Alumis Inc. is an equal opportunity employer.

We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.